Desde 2006 que os jogos do Guitar Hero têm feito os jogadores sentir-se como o Eddie Van Halen. Com este novo lançamento, também podes viver a fantasia de te tornares Keith Moon e Liam Gallagher com o conjunto incluído de bateria e microfone.
A juntar-se à experiência de banda total tens o Music Studio, que permite aos jogadores criarem as suas próprias faixas originais e partilhá-las com outros jogadores de todo o mundo.
Após algum tempo no estúdio, podes levar a tua banda em digressão e competir com outros jogadores numa Batalha de Bandas através da Rede PlayStation.
311 - “Beautiful Disaster”
30 Seconds To Mars - “The Kill”
Airbourne - “Too Much Too Young”
The Allman Brothers Band - “Ramblin Man”
Anouk - “Good God”
The Answer - “Never Too Late”
At The Drive-In - “One Armed Scissor”
Beastie Boys - “No Sleep Till Brooklyn”
Beatsteaks - “Hail to the Freaks”
Billy Idol - “Rebel Yell”
Black Label Society - “Stillborn”
Black Rebel Motorcycle Club - “Weapon of Choice”
blink-182 - “Dammit”
Blondie - “One Way or Another”
Bob Seger & The Silver Bullet Band - “Hollywood Nights”
Bon Jovi - “Livin’ On A Prayer”
Bullet For My Valentine - “Scream Aim Fire”
Coldplay - “Shiver”
Creedence Clearwater Revival - “Up Around The Bend”
The Cult - “Love Removal Machine”
Dinosaur Jr. - “Feel The Pain”
The Doors - “Love Me Two Times”
Dream Theater - “Pull Me Under”
The Eagles - “Hotel California”
The Enemy - “Aggro”
Filter - “Hey Man, Nice Shot”
Fleetwood Mac - “Go Your Own Way”
Foo Fighters - “Everlong”
The Guess Who - “American Woman”
Hush Puppies - “You re Gonna Say Yeah!”
Interpol - “Obstacle 1”
Janes Addiction - “Mountain Song”
Jimi Hendrix - “Purple Haze (Live)”
Jimi Hendrix - “The Wind Cries Mary”
Jimmy Eat World - “The Middle”
Joe Satriani - “Satch Boogie”
Kent - “Vinternoll2”
Korn - “Freak On A Leash”
Lacuna Coil - “Our Truth”
Lenny Kravitz - “Are You Gonna Go My Way”
Linkin Park - “What I ve Done”
The Living End - “Prisoner of Society”
Los Lobos - “La Bamba”
Lost Prophets - “Rooftops (A Liberation Broadcast)
Lynyrd Skynyrd - “Sweet Home Alabama (Live)”
Mars Volta - “L Via L Viaquez”
MC5s Wayne Kramer - “Kick Out The Jams”
Metallica - “Trapped Under Ice”
Michael Jackson - “Beat It”
Modest Mouse - “Float On”
Motörhead - “Overkill”
Muse - “Assassin”
Negramaro - “Nuvole e Lenzuola”
Nirvana - “About a Girl (Unplugged)”
No Doubt - “Spiderwebs”
NOFX - “Soul Doubt”
Oasis - “Some Might Say”
Ozzy Osbourne - “Crazy Train”
Ozzy Osbourne - “Mr. Crowley”
Paramore - “Misery Business”
Pat Benatar - “Heartbreaker”
R.E.M. - “The One I Love”
Radio Futura - “Escuela De Calor”
Rise Against - “Re-Education Through Labor”
Sex Pistols - “Pretty Vacant”
Silversun Pickups - “Lazy Eye”
Smashing Pumpkins - “Today”
Steely Dan - “Do It Again”
Steve Miller Band - “The Joker”
Sting - “Demolition Man (Live)”
The Stone Roses - “Love Spreads”
Stuck In The Sound - “Toy Boy”
Sublime - “Santeria”
Survivor - “Eye of the Tiger”
System of a Down - “B.Y.O.B.”
Ted Nugent - “Stranglehold”
Ted Nugents Original Guitar Duel Recording
Tokio Hotel - “Monsoon”
Tool - “Parabola”
Tool - “Schism”
Tool - “Vicarious”
Trust - “Antisocial”
Van Halen - “Hot For Teacher”
Willie Nelson - “On The Road Again”
Wings - “Band on the Run”
Zakk Wyldes Original Guitar Duel Recording